As of the 4/1/12 I have been on Duromine for 3 weeks.
In the first week I experienced headaches, sleeplessness and a dry mouth.
I was able to control the headaches with lots of water and panadol when needed.
By the second week I had constipation , but that is starting to ease now, not as regular as I would like, but I am at leaset able to go.
My altered sleep pattern had also settled a little by 2 weeks, but have found winding down at night by either laying in bed playing on my phone or watching a movie helps me nod off. I still experience a dry mouth now and then, so I always have water on hand.